The treatment of AIDS mainly includes general symptomatic support therapy, antiviral therapy and complications treatment. With the development and innovation of therapeutic drugs, AIDS has changed from a fatal disease to a chronic disease that can be managed for a long time.
Treatment cycle: AIDS is currently incurable and requires lifelong intermittent treatment.
General treatment: asymptomatic HIV infected people can maintain normal work and life. For patients with or without AIDS, attention should be paid to rest and nutrition, giving high calorie, high vitamin diet, and those who can not eat. In addition, it is necessary to give symptomatic blood transfusion and maintain water and electrolyte balance. For patients who have controlled their condition, antiviral treatment can be carried out according to the specific condition and their personal wishes, and the changes of the condition can be closely monitored.
Drug therapy: nucleoside and nucleotide reverse transcriptase inhibitors, such as zidovudine, lamivudine, tenofovir, abacavir and ntrutabine, have definite curative effect and high activity against retroviruses including human immunodeficiency virus (HIV) in vitro.
Non nucleoside reverse transcriptase inhibitors, such as irvavirin, nevirapine and ribavirin, are first-line drugs for the treatment of AIDS, which can effectively prevent viral transcription and replication.
Protease inhibitors, such as lopinavir + ritonavir and darunavir, can effectively block the formation of infectious virus particles.
Other drugs: integrase inhibitors, such as dotilavir and latilavir, and some drugs are mixtures, such as propofol tenofovir + ntriptabine + iveravir + cobistat, dotilavir sodium + abacavir sulfate + lamivudine, can effectively control the progress of the disease.
Surgical treatment: there is no surgical treatment for the disease.
1,For oral Candida infection, grind nystatin and add glycerol, adjust it into a paste, apply it locally, or adjust it into a viscous paste and swallow it slowly.
2,Pneumocystis carinii pneumonia, oral compound sulfamethoxazole, after recovery, it needs to be taken intermittently to prevent recurrence. Pay attention to hemogram, urine routine and renal function when taking it for a long time.
3,Bacterial infection, recurrent Salmonella infection. If the blood culture is positive, oral quinolones can be taken. Isoniazid, rifampicin, pyrazinamide, streptomycin or ethambutol triple or quadruple antituberculosis drugs can also be used for intensive treatment for 2 months, and isoniazid and rifampicin for consolidation treatment for 4 months. Liver and kidney function should also be monitored during medication.
4,Cryptococcal meningitis. The focus of treatment is to reduce intracranial pressure. 20% mannitol or ventricular drainage can be used, and amphotericin B can be used as antibiotics.
5,Herpes virus infection, herpes zoster can take acyclovir or valaciclovir orally, herpes simplex or cytomegalovirus infection can take acyclovir or valaciclovir orally.
6,For toxoplasmosis, oral sulfadiazine or pyrimidine is the first choice for pathogen treatment, and antibiotics can be used as an alternative treatment.
7,Cryptosporidiosis, rehydration, correction of electrolyte disorder and regulation of immune function, oral spiramycin or oral metronidazole.
8,Tumor. For Kaposi sarcoma with rapid development, vincristine, bleomycin or adriamycin can be used in combination.
Prognosis: AIDS can not be cured at present. If the patient is actively treated, it can delay the progression of the disease. If the patient can not tolerate drugs or not adhere to regular medication, leading to further decline in immune function, the development of AIDS process, can lead to serious complications, eventually leading to death.
How long will it last? The prognosis of AIDS is closely related to whether the patient is treated or not. If the patients do not have antiviral treatment or have poor compliance with the virus treatment, the patients will enter the AIDS period after the incubation period, and there will be various opportunistic infections during the AIDS period. Eventually, it will cause death due to opportunistic infection and malignant tumor. The survival period of AIDS patients is only 12~18 months. If the patient can insist on taking antiviral drugs and go to the hospital for follow-up visit regularly, the patient can inhibit the virus for a long time, the cd4-t lymphocytes in the body can also be maintained at the level of normal people, and the patient can work, live and study completely like normal people.
Re visit: AIDS patients in the treatment of antiretroviral treatment, first months to the hospital for treatment two times, second months and third months of each visit once again, 3 months later, if there is no obvious adverse reactions, every quarter for a visit, if there is any discomfort, should be re examined at any time.