Acute symptoms: fever, fatigue, sore throat, general discomfort and other symptoms of upper respiratory tract infection usually occur 1 ~ 2 weeks after exposure to HIV; Some patients have headache, rash, meningoencephalitis or acute multiple neuritis; There are enlarged lymph nodes in the neck, armpit and occipital part, similar to infectious mononucleosis or hepatosplenomegaly.
Asymptomatic symptoms: often without obvious symptoms and signs, some patients may have persistent lymphadenopathy and maintain it for a long time.
AIDS symptoms: unexplained low immune function; Continuous irregular low heat for more than 1 month; Persistent unexplained systemic lymphadenopathy (lymph node diameter greater than 1cm); Chronic diarrhea more than 4 ~ 5 times / day, weight loss more than 10% within 3 months; Oral candidal infection, Pneumocystis carinii pneumonia, cytomegalovirus infection, toxoplasmosis, cryptococcal meningitis, rapidly developing active pulmonary tuberculosis, lymphoma, etc; Dementia occurs in young and middle-aged patients.
Other symptoms: 90% of HIV infected patients or AIDS patients in the course of skin lesions, can be manifested as infectious skin lesions, non infectious skin lesions and skin tumors.
Non infectious skin damage: the skin lesions are pleomorphic, which can be similar to seborrheic dermatitis, ichthyosis, hairy red pityriasis, psoriasis, etc., but the condition is usually more serious. In addition, atopic dermatitis, photosensitive dermatitis, pityriasis rosea, urticaria, erythema multiforme and acne like lesions can also appear.
Infectious skin damage:
1,Herpes zoster often involves a large range, including blisters, bullae and blood blisters. It has severe pain and is very prone to secondary bacterial infection, which can cause encephalitis, pneumonia and even death.
2,Herpes simplex often recurres frequently, and the distribution of skin lesions is localized or disseminated. It is manifested as persistent severe herpes in the mouth, genitals and perianal area, which can not heal for a long time and form deep ulcer.
3,Wart, which can be manifested as common wart, flat wart and infectious soft wart. Male homosexual patients often have condyloma acuminatum around the anus and rectum.
4,Fungal infection and thrush are the earliest symptoms of immune deficiency. In addition, more serious superficial fungal infection often occurs, such as generalized tinea corporis and cruris, tinea manus and pedis and multiple onychomycosis. Sometimes the performance is not typical, and fungal microscopic examination and culture are needed.
5,Bacterial infection, manifested as folliculitis, multiple skin abscesses or boils.
1,Kaposi’s sarcoma is common at the tip of the nose, oral mucosa, trunk and limbs. The skin lesions begin with pink spots, and the long axis is consistent with the direction of the dermatoglyphs. Later, the color darkens, forming lavender or brown spots or plaques, and finally become hemorrhagic lesions and nodules.
2,Lymphoma and skin lesions are nonspecific and can be papules or nodules. The diagnosis mainly depends on pathology.
1,Due to low immune function, patients with bacterial infection and virus infection are easy to be complicated with various pathogenic bacterial infections, such as bacterial infection, virus infection and fungal infection.
2,Malignant tumor, the patient’s immune system is damaged, which is easy to be complicated with malignant tumors, such as Kaposi’s sarcoma, lymphoma, etc.