Intravenous infusion therapy is a highly professional technology. Its treatment level covers parenteral infusion, nutritional support, medication and infusion. Looking back on its history, it began in the 17th century, but the great progress mainly occurred in the 20th century. What are the major inventions during this period? We can review the history of infusion, catheter and dressing to understand how these inventions improve the living space and care quality of patients.
The earliest record of treating diseases with blood was in 1492, when the blood of three boys was given to Pope III, but it was not until 1615 that libavious reintroduced the concept of blood transfusion from one person to another, but it was not practical at that time. The concept of blood transfusion is the beginning of intravenous therapy. After several centuries, blood transfusion between people became possible, and it took a longer time for safe blood transfusion technology to appear.
Progress of infusion
Modern intravenous therapy originated in the 19th century, which was the century of great development of medicine. The first great achievement was in 1818, when James Blundell gave the first blood transfusion between people in London. In 1834, Blundell gave another blood transfusion between people. A pregnant woman was dying due to bleeding. Therefore, Blundell further believed that the blood loss caused by bleeding was related to low blood volume
A cholera epidemic occurred in Scotland in 1831, which was also an important event in the development of intravenous therapy. In this epidemic, Thomas Latta experimentally injected saline solution into a patient. At that time, the patient was “dying, and nothing will hurt him. In fact, he has lost weight. I’m afraid he will lose his breath before I have prepared the tools”. But Latta’s treatment was successful, and the patient finally recovered and survived. The success of saline injection makes this therapy widely used in cholera epidemic, but its success rate is limited. More work has been done since then.
In 1900, Landsteiner found that when different human blood was mixed, it would react. This major discovery finally led to the confirmation of human ABO blood group system. In the history of blood transfusion treatment, the Second World War played a very important role, because the application of blood transfusion during the war was more common than ever before. Out of necessity, blood transfusion must be given to injured soldiers to save more lives. Therefore, today, blood transfusion treatment is a general medical technology, and blood can be separated into various components, The corresponding blood components required by the patient can be input separately according to the specific components that the patient lacks.
In the 20th century, parenteral nutrition (TPN) support has also made significant development. Dr. Stanley Dudrick, the father of parenteral nutrition, successfully injected high concentrations of glucose and protein into the subclavian superior vena cava in 1967. Due to this breakthrough, the concept of central venous therapy (CVC, commonly known as CVP) has sprung up, creating the invention and revolution of all kinds of central catheters and dressings.
What is intravenous infusion
Injecting a large amount of liquid, electrolyte or blood through the vein is called intravenous infusion. Due to the different injection site and infusion, it can be divided into peripheral venous infusion, central venous infusion, high nutrition infusion (TPN) and blood transfusion.
Advantages of intravenous infusion
1,It is easy to reach the therapeutic concentration of the drug and maintain the constant concentration required for the efficacy.
2,Drugs that stimulate muscle and subcutaneous tissue can be given intravenously.
3,It can quickly replenish the fluid or blood lost by the body.
4,Intravenous nutrition infusion.
Disadvantages of intravenous infusion
1,Improper treatment is easy to produce systemic or local infection.
2,Drug overdose or rapid infusion is easy to produce adverse reactions and even life-threatening.
3,Continuous excessive infusion is easy to cause excessive circulating load or electrolyte imbalance.
4,The increase of iatrogenic diseases.