Amoxicillin: the number one anti-inflammatory drug?

alopah Date:2021-08-11 11:27:19
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“I take amoxicillin whenever I get a cold, there won’t be any problem, right?” Many people’s questions. In this regard, doctors have made relevant interpretations.


Amoxicillin is not the drug of choice for colds and fevers


Amoxicillin is a penicillin antibiotic that is widely used and has a strong and rapid bactericidal effect, and is not easily affected by most foods and is completely absorbed. It accounts for more than half of the use of antibiotics in hospital outpatient clinics. Its preparations include capsules, tablets, granules, dispersible tablets and so on. The commonly used tablets are 0.125g and 0.25g; capsules are 0.125g, 0.25g and 0.5g; three sizes; and the size for injection is 0.5g each.


Regardless of the dosage form of amoxicillin, the storage environment is very demanding and should be shaded, sealed and kept in a cool, dark and dry place. Many people place the drug as they do with sundries, where it is convenient to put it, and even place amoxicillin closer to heat sources such as stoves and heaters, which is very prone to deterioration.


Amoxicillin is suitable for infections caused by sensitive bacteria, such as otitis media, sinusitis, pharyngitis, tonsillitis and other upper respiratory tract infections caused by Streptococcus hemolyticus, Streptococcus pneumoniae, Staphylococcus or Haemophilus influenzae, lower respiratory tract infections such as acute bronchitis and pneumonia, and for genitourinary tract infections caused by Escherichia coli, Streptococcus mirabilis or Enterococcus faecalis, Streptococcus hemolyticus, Staphylococcus or Escherichia coli It is also used for genitourinary tract infections caused by Streptococcus haemolyticus, Staphylococcus or Escherichia coli, and for acute simple gonorrhea. In addition, amoxicillin can be used in triple combination with clarithromycin and lansoprazole to eradicate H. pylori from the stomach and duodenum and reduce the recurrence rate of peptic ulcers.




Amoxicillin is not the drug of choice for respiratory diseases. In fact, amoxicillin does not work for viral colds and fevers. Most respiratory illnesses such as colds and fevers in life are caused by viruses, and no amoxicillin is needed for that symptom; only bacterial infections require amoxicillin. In fact, amoxicillin is most suitable for digestive tract diseases, such as abdominal pain and ulcers. For example, amoxicillin 500mg, metronidazole 0.2g three times a day, and omeprazole 10mg once a day for four weeks is a course of treatment, which can well relieve the symptoms of stomach diseases and also repair the gastric mucosa as well as the damaged parts of the stomach and reduce the side effects produced by western medicine. In addition, the antibacterial effect of amoxicillin is significantly enhanced when it is combined with β-lactamase inhibitors such as clavulanic acid, especially it can enhance the effect of amoxicillin on non-susceptible strains such as Bacillus mimicus, Legionella, Nocardia and Bacillus pseudonasalis.


The drug should be taken after meals to reduce gastrointestinal reactions. Do not eat high-fiber foods, such as oats, celery, and carrots, while taking the drug, as this may reduce its effectiveness. In addition, amoxicillin is contraindicated with gentamicin, kanamycin, ciprofloxacin and pefloxacin, and should not be put in the same container when combined.


Amoxicillin is not a necessary medicine


Nowadays, more and more people take amoxicillin as a necessary medicine at home, which is a special medicine for headache and brain fever. In fact, amoxicillin is a broad-spectrum antibiotic that is effective against many pathogenic bacteria, but it must be used under the guidance of a professional doctor, and it is both blind and dangerous to take it as a family medicine. Long-term abuse can lead to a vicious circle, in addition to allergic symptoms, the burden on the liver, and in serious cases, even no drugs available.


In order to prevent the occurrence of serious allergic reactions, a detailed past medical history must be inquired before amoxicillin administration, including the history of drug use, whether penicillin-like drugs have been used, whether there are symptoms of reactions easily ignored by patients, such as chest tightness, itching, facial numbness, fever, etc., and whether there are individuals or families with allergic diseases.


Penicillin skin test must be performed before using amoxicillin, and positive reactions are prohibited. Clinically, the incidence of adverse reactions to amoxicillin is about 5%, mostly seen in allergic reactions such as urticaria, rash and asthma, or symptomatic digestive symptoms such as diarrhea, nausea and vomiting, as well as side effects such as anemia, convulsions, excitement, anxiety, insomnia and dizziness. If any of these adverse reactions occur during the course of taking amoxicillin, the drug must be discontinued immediately.


Use with caution in pregnant and nursing women and children under 3 months of age because amoxicillin can be excreted in small amounts through breast milk and there is a risk of allergy in the infant when amoxicillin is used by the nursing mother. When amoxicillin is combined with contraceptives, it can interfere with the enterohepatic circulation of the contraceptives, thus reducing their efficacy. Other studies have suggested that chloramphenicol, macrolides, Juanamides and tetracyclines, have the potential to interfere with the antibacterial effects of amoxicillin in vitro.


Oral formulations of amoxicillin are used only for mild to moderate infections. In case of overdose, supportive treatment and symptomatic treatment are available. For dosage, adults should take 0.5g once every 6~8 hours at a daily dose not exceeding 4g when taken orally; pediatric patients should take 20~40mg/kg daily at a daily dose every 8 hours. For the treatment of acute urinary tract infection without complications, a single oral dose of 3g of this product can be given, or an additional dose of 3g can be given 10~12 hours later. Neonates and preterm infants can be treated with 50mg orally once every 12 hours, or once every 8 hours if the infection is severe. For intramuscular injection or intravenous drip after dilution, 0.5~1g once, 3~4 times a day; for children, 50~100mg/kg daily, divided into 3~4 intravenous doses.


Buying amoxicillin to eat when you have a cold is actually an abuse of antibiotics. Many people have the habit of taking antibiotics like amoxicillin as soon as they find out they have a cold and feel a sore throat and cough. In fact, most colds are caused by viruses, and taking antibacterial agents that deal with bacteria is not effective. Only after the cold continues to develop and is complicated by bacterial infections can you use antibacterial agents.

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