There are seven kinds of daily sartan antihypertensive drugs, including valsartan, losartan, irbesartan, olmesartan, telmisartan, candesartan and alisartan; Although they are both sartan antihypertensive drugs, their country of origin, research and development place and dosage are different. Let’s have a look.
The original research enterprise is ruohua pharmaceutical, Switzerland. The usual dosage is 80mg / day. Generally, the drug effect reaches the peak concentration two hours after taking it, and the average half-life is 9 hours. It can be attributed to the class of long-acting antihypertensive drugs. Generally, it needs to be taken continuously for two to four weeks to achieve the maximum antihypertensive effect; In China, the maximum dose of valsartan is 160mg / day.
The original research enterprise is mercodon, an American pharmaceutical company, and the usual dosage is 50mg / day; Generally, the drug effect reaches the peak three to four hours after taking, with an average half-life of 6 to 9 hours. Generally, the best antihypertensive effect can be achieved only after taking it for three to six weeks; At the same time, it also has a function of reducing uric acid; In China, the maximum dosage of losartan is 100mg / day.
The original research enterprise is a French pharmaceutical company, the development of the drug companies, generally take one to 1.5 hours after the peak efficacy, the average half-life of 11 to 15 hours, generally continue to take four to six weeks to achieve the best antihypertensive effect, irbesartan for some diabetic patients, diabetic nephropathy, diabetic proteinuria patients have certain test evidence. In China, the maximum allowable dose of irbesartan is 300mg / day.
The original research enterprise is the research and development of the first Sangong pharmaceutical enterprise in Japan. It reaches the peak one to two hours after taking it, with an average half-life of 13 hours. It continues to take it for one to two weeks to achieve the maximum antihypertensive effect. The maximum dose allowed in China is 40mg / day.
The original research enterprise is developed by Boehringer Ingelheim, Germany. The peak efficacy can be reached within half an hour to one hour after taking it. The half-life of more than 20 hours can achieve the antihypertensive effect after taking it for four to eight weeks. The maximum allowable dose in China is 80mg / day.
The original research enterprise, Takeda pharmaceutical research and development, reaches the peak three to four hours after taking, with an average half-life of 9 hours. The best antihypertensive effect can be achieved only after taking it for about two weeks. The maximum dose allowed in China is 8mg / day.
It is made in China and developed by Shenzhen xinlitai Pharmaceutical Co., Ltd. it reaches the peak one hour to one and a half hours after taking it, with an average half-life of 10 hours. It has the best antihypertensive effect after taking it for two to four weeks. It also has the effect of slightly reducing uric acid. The maximum dose is 240mg / day.
None of the seven sartan antihypertensive drugs has a good effect, and which one has a bad effect, the medication should follow the doctor’s advice; While taking symptomatic drugs, we also need to pay attention to our own living habits, diet, exercise, auxiliary conditioning and so on.