Aspirin has long been widely used as an antipyretic and analgesic around the world, with 50,000 tons and over 200 billion tablets consumed globally every year. Because of the huge number of people taking aspirin, there are often questions in the background: “When is it better to take aspirin? Is it better to take it on an empty stomach, or after a meal? Is it better to take it in the morning or at night before going to bed?” “What should I do if I get a stomachache after taking aspirin? Can I stop taking it?”
In response to these common questions that we all care about, here are some detailed answers. First of all, let’s understand aspirin as a medicine.
What diseases can aspirin treat?
The role and efficacy of aspirin includes two main aspects：
Aspirin is a non-steroidal anti-inflammatory drug, so it has an anti-inflammatory effect and can reduce pain and fever caused by inflammation, so it has an antipyretic and analgesic effect, and is commonly used in the antipyretic treatment of febrile diseases and the pain relief treatment of painful diseases.
Second, small doses of aspirin also have an anti-platelet aggregation effect, which is often used clinically to prevent thrombosis caused by platelet aggregation, so it is often used in the treatment of atherosclerotic cardiovascular diseases to prevent the occurrence of thrombotic cardiovascular events.
In clinical practice, aspirin should be used in a rational manner according to its pharmacological characteristics.
How to take aspirin correctly?
At present, the vast majority of aspirin used for the prevention of cardiovascular events are enteric-coated tablets. This reduces the direct stimulating effect on the stomach and is best taken before a meal. However, if it is a generic preparation it should still be taken after a meal, so that the aspirin is mixed with food, which reduces the direct damage to the gastric mucosa.
Is it better to take it in the morning or in the evening For this issue, no clear rules have been made. As for whether to take it in the morning or in the evening, there is not much difference, the main thing is to take it every day, and it is important to adhere to it. In addition, the aspirin preparation currently used for clinical prevention and treatment of cardiovascular and cerebrovascular diseases is enteric tablets, remember not to break open to eat, otherwise it will increase the side effects of the gastrointestinal tract.
Some patients taking aspirin are often troubled by its side effects, such as gastrointestinal adverse reactions, etc. What should be done in this situation?
Scientific use of medication to reduce side effects
1,nausea, acid reflux, heartburn, indigestion and other gastrointestinal reactions
Gastrointestinal adverse reactions such as nausea, acid reflux, heartburn and indigestion are common after taking aspirin. Patients should first confirm whether the method of taking aspirin is correct. If the method of taking aspirin is improper, the method of taking aspirin should be corrected first, and then observe whether there are still symptoms of gastrointestinal discomfort. If the method of administration is correct, a stomach protector can be added to reduce gastrointestinal reactions. If the gastrointestinal reaction is more obvious and there is still discomfort with the addition of stomach protector, clopidogrel can be considered as an alternative treatment.
2,Gastrointestinal bleeding such as black stool, bloody stool, or even vomiting blood
Be sure to watch for black stools after taking aspirin. This is a symptom of upper gastrointestinal bleeding. If the bleeding is more frequent and serious, there will be bloody stools or vomiting blood. In this case, you should stop using the drug immediately and go to the hospital promptly.
It is important to know that aspirin is known as a “miracle drug” in time, but it is also a double-edged sword. Authoritative clinical studies have shown that long-term use of low-dose aspirin can reduce the risk of death from cardiovascular disease by nearly 40%, and in most cases the benefits of taking aspirin far outweigh the possible adverse effects.
However, as a precautionary measure, the following conditions or populations should be taken with caution, and the need for the drug should be determined by the physician in the context of clinical risk and benefit.
Aspirin should be chosen with caution in the following situations or groups
Patients with bleeding tendency, bleeding disorders or low platelets; patients with peptic ulcer or reflux esophagitis; patients using vitamin B1, certain hypoglycemic drugs, other anticoagulants.